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Session will examine how modulating the microbiome can affect rheumatoid arthritis
The microbiome presents a tremendous opportunity for understanding disease because it’s able to be manipulated once you find the right way, but there’s still so much unknown about finding the right way to manipulate the microbiome.
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FDA leaders will address challenges and opportunities in pediatric study designs
The FDA is employing extrapolation of adult efficacy data in drug development programs in rheumatology conditions that demonstrate a similar disease pathophysiology and clinical presentation, similar co-morbidities, and similar response to therapy in pediatric rheumatology patients to achieve the goal of shortening timelines for pediatric…
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Studies look at whether preclinical treatment may delay, prevent RA
Research continues into finding ways to treat rheumatoid arthritis early enough to delay the onset of symptoms or possibly reverse the course of the disease entirely and keep arthritis from developing.
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New molecular targets could advance OA treatment
Only in the past 15 years or so have people accepted the idea that molecular targeting could lead to disease modification in osteoarthritis, and an ACR Convergence 2020 educational session will cover the latest targets in preclinical models and early phase trials involving both mice…
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Mothers with rheumatic diseases need more support from healthcare providers
The education session Reproductive Health: Meet Women’s Needs features three speakers who not only work with patients with rheumatic disease but are also mothers who live with a rheumatic disease.
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Kristina Clark, MD, MRCP: Blister fluid and plasma in systemic sclerosis
MEET THE POSTER PRESENTER: SSc is a severe rheumatic disease with high mortality from lung and heart disease, and major non-lethal clinical burden, including fibrosis of the skin. Sampling skin gives a unique opportunity to explore local disease mechanisms and better understand pathogenesis.
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Pamela Weiss, MD, MSCE: Axial disease criteria development for juvenile SpA
MEET THE POSTER PRESENTER: The objective of this study was to identify and grade a set of items that maximizes the likelihood of accurate classification of children and adolescents with axial disease.
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Bates Gribbons: Leukocyte Populations in Takayasu’s Arteritis and Giant Cell Arteritis
MEET THE POSTER PRESENTER: We identified that absolute monocyte count was associated with vascular inflammation as measured by 18F-fluorodeoxyglucose positron emission tomography (FGD-PET) in Takayasu’s arteritis and giant cell arteritis.
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Experts debate when to use JAK inhibitors to treat RA
Growing data suggests that JAK inhibitors may be more effective than TNF inhibitors for the treatment of RA. The Great Debate asked, is it time to revisit the ACR guideline?
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Year in Review highlights top clinical, basic science papers
The 2020 version of the Year in Review included looks at positive lupus trial results and high-dimensional profiling by single-cell RNA-sequencing.