THE OFFICIAL NEWS SOURCE OF ACR CONVERGENCE 2022 • NOVEMBER 10-14



Nicholas Sumpter, MS: Transition from hyperuricemia to gout

Poster presenter: Nicholas Sumpter, MS, University of Alabama at Birmingham

Poster title: Genetic Effects on the Transition from Hyperuricemia to Gout

Poster Session D
8:30 – 10:30 a.m. ET Tuesday, Nov. 9
All ACR Convergence 2021 poster presentations are available on demand to registered meeting participants through March 11, 2022.

What is your poster about?
This study aimed to provide alternative explanations for findings from several recent hyperuricemia-to-gout genome-wide association studies that claimed identified loci had a potential inflammatory role in gout.

Why did you decide to investigate this topic?
We had seen several publications using this technique without much regard for whether it truly captures what they claim it captures.

What are you working on next related to this research?
We are going to work on establishing a more reliable metric for hyperuricemia based on multiple measurements. We will also try to reproduce existing studies with this more reliable measure.

What excites you most about your work?
The potential to improve the accuracy of the field going forward, and to potentially identify inflammatory genes associated with gout that could become drug targets or aid prediction of gout.